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SYSTEMATIC REVIEW

Depression and Anxiety among Adolescents with Type 1 Diabetes Mellitus: Systematic Review of Literature

The Open Nursing Journal 12 Sept 2025 SYSTEMATIC REVIEW DOI: 10.2174/0118744346393599250908085129

Abstract

Introduction

Type 1 Diabetes Mellitus (T1DM) is one of the most prevalent chronic endocrine diseases among adolescents in the world. Studies reported that adolescents with T1DM complain of anxiety and depression. The current study aims to review depression and anxiety among adolescents with T1DM.

Methods

A literature review was conducted using the MEDLINE, PubMed, Google Scholar, and Science Direct Databases, with the following keywords: “Type 1 Diabetes Mellitus,” “Adolescents,” “Depression,” and “Anxiety.” The search included published studies between 2011 and 2024.

Results

Sixteen articles were included in the current review. The findings indicated high levels of anxiety and depression among adolescents with T1DM, which were associated with poor glycemic control and elevated HbA1c levels. Female adolescents with T1DM were associated with a higher level of anxiety and depression than males.

Discussion

This systematic review emphasizes the importance of integrated mental health support in diabetes care for adolescents with T1DM.

Conclusion

Healthcare providers should screen for depression and anxiety, use multidisciplinary approaches, and involve schools and families in fostering a supportive environment.

Keywords: Type 1 diabetes, Adolescent depression, Anxiety, Literature review, Anxiety, Depression.
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