Nurses’ Knowledge toward Hepatitis B and Hepatitis C in Guilan, Iran

INTRODUCTION

Hepatitis B (HBV) and C (HCV) are two common, serious causes of chronic liver disease and liver damage. The World Health Organization (WHO) has reported that more than 500 million people are living with chronic viral hepatitis in the world [1, 2]. Since,50% to 80% of HCV infection leads to chronic hepatitis [3, 4], the increasing burden of HCV infection is considerable. In addition, an estimate of 57% of liver cirrhosis and 78% of liver cancer are considered due to hepatitis B virus (HBV) or hepatitis C virus (HCV) infections [1, 2]. The Middle East country and Iran located in the intermediate endemicity with a carrier rate between 2% and 8% [5]. Percutaneous injuries are one of the most common routes of HBV and HCV [6, 7]. According to the WHO, about three million individuals are injured per year due to needle stick or sharps injuries [8]. Health-care workers(HCWs) including nurses are potentially at high risk of blood-borne diseases such as HBV or HCV. Studies reported the risk of pathogens transmission HCWs by a needle stick injury (NSI) has been estimated to be between 6% and 30% for HBV and between 3% and 10% for HCV [9]. An average seroconversion rate for HCV in occupational exposure has been estimated 1.8% (range: 0-7%) [10]. Although NSI hepatitis seroconversion is somewhat rare, the costs of treatment and anxiety about the possible consequences of an exposure are serious. In this area, prevention through immunization and increasing knowledge are the safe strategy against the high prevalence of viral hepatitis among HCWs. For this reason, some HCWs refuse to service patients with blood born disease such as HIV/AIDS, HBV and HCV [11-14]. On the other hands, several studies reported the nurses who are informed about the mode of HBV and HCV transmission will have a positive attitude and confidence in treating or handling patients [11-15]. Hence, HCWs should familiarize themselves with guideline designed to prevent transmission of HBV, HCV and other blood-borne pathogens. The purpose of this study was to assess knowledge towards HBV and HCV among nurses in different hospitals of Guilan University of Medical Sciences, Rasht, Iran.

MATERIALS AND METHODOLOGY

A questionnaire based cross- sectional study was conducted in various teaching hospitals setting of Rasht, the capital city of Guilan province, North of Iran. All study hospitals provide tertiary health-care level to a large population of Guilan province. All HCWs agreed to participate and filled in the questionnaire were included in the study. The participants were asked to complete a Self-report questionnaire separately under supervision of a trained research assistant. Sample enrollment, data gathering and data entry were supervised by aresearch assistant.

We used the Richmond et al. [15] self report questionnaire with some modifications. In our previous research, the face and content validity of the developed and standardized questionnaire was determined by a panel of experts of Gastrointestinal and Liver Diseases Research Center (GLDRC) of Guilan University of Medical Science (GUMS) [7]. This specifically designed questionnaire has been reported to be acceptable to almost all responders in a pilot study, with a cronbach's alpha coefficient of 0.7 for HBV knowledge and alpha = 0.8 for HCV knowledge. The questionnaire consisted of 70 questions and 3 main parts (including 22 questions on demographic data, job category, HBsAb, vaccination status, family history of HCV or HBV and history of NSI, 26 questions on the knowledge about HBV and 22 about level of knowledge on HCV infection. Knowledge section for HBV and HCV included the following category focusing on :A) nature of disease, consisted of 5 statements B) modes of transmission consisted of 11 statements for HBV and 10 statements for HCV C) Ways of preventing HBV and HCV infection consisted of 5 statements and D) treatment of HBV and HCV consisted of 2 statements . Hepatitis B questionnaire had an additional three questions about the availability of vaccine. Knowledge questions were propositions to which true/false/do not know could be replied. The total knowledge score of the participants was calculated by giving one point to each correct answer with a maximum possible score of 26 for HBV and 22 for HCV and minimum score of zero. The aim of the study was explained to participants, and were asked namelessly responded to the questionnaire.

The study design and written informed consent (per the Helsinki declaration) were approved by the ethics committee of the gastrointestinal and liver diseases research center of Guilan University of Medical Sciences.

RESULTS

DISCUSSION

In the present study, among all study participants less than half had satisfactory knowledge about HBV and HCV. In the same way, in several study HCWs’ knowledge toward HBV and HCV were relatively low [16-20]. Majority of responders reported good knowledge about mode of transmission toward HBV and also HCV. A small percentage of respondents actually knew about nature of disease, prevention and treatment strategy. Our results are in line with the findings from studies reported majority of medical students and HCW had correct knowledge on transmission mode [16, 17, 21]. Yamazhan et al. in a multi-centre cross-sectional study showed that nursing students had a low level of knowledge about nature of the disease and its complications [22].

The most important source of information was through book and educational class and unsurprisingly HCWs with higher educational level were more aware about HBV. Responders’ knowledge score in all domains were higher than among advanced educational level. Our results are in line with the findings from studies reported more educated worker related with more knowledge toward HBV and HCV [15, 23, 24]. Setia et al. investigated awareness toward HBV and HCV amongst HCWs of a tertiary level hospital in India, indicated nursing students’ knowledge was considerably lower than the dental and medical students [24] As well as, a study in Turkey indicated that mean knowledge score was significantly higher in fourth-year students than third-year students [25].

Several studies tried to show the effect of HCWs training on knowledge to viral hepatitis, reported participants who received more education showed considerable improvement in their knowledge levels [6, 26, 27].Therefore, providing more education course can help health staff to remember the preventative measure.

In the current study, almost half of the HCWs had history of NSI whereas 93% of them pass educational course about NSI. Perhaps the reason for the such high rate of NSI in spite of passing education was carelessness because of high workload. Similarly, Joukar et al. in a survey showed 54% of health care professionals had a history of NSI [7]. In another study, nurses who had NSI history showed considerably higher knowledge scores toward HBV, while knowledge score concerning having NSI history in our study was not different.

We reported similarity in total knowledge score toward HBV concerning work experience, but more experienced worker mentioned better score in questions related vaccine availability and treatment strategy. Joukar et al. in their study declared the mean score between the work experience groups was similar [7]. This finding indicate the result of repeated educational course during work years. Abozead et al. reported the high frequency of NSIs among HCWs while, more than 60% of nurses did not pass any educational program about viral hepatitis immunity and control [28]. In the same way, Askarian et al. in a cross-sectional study revealed 71.1% of the students had NSIs, unfortunately 82% of them did not reported and worked up [29]. Our study participants who had history of immunization were more knowledgeable about HBV, especially in relation to mode of transmission, vaccine availability and treatment strategy. Responders with history of education about NSI showed the higher score about nature of HCV.

Our study revealed a similarity in knowledge score at the eight university teaching hospitals, and also, the mean score of the all eight hospital were less than mean total score. This finding may be due to insufficiency of educational program in the hospital setting especially after graduation. Awareness levels derived from previous survey were unsatisfactory in all HCWs even medical students. Despite, the majority of HCWs passed the educational program, they showed unsatisfactory knowledge on causative agents, mode of transmission, symptoms and prevention strategy. As well as, a high frequency of NSIs reported in health staff. Hence, extensive and effective continuing health educational course should be provided to health staff. Health staff should be sensitive and responsible for own health and wellbeing creating a culture of self-care among HCW, vaccine availability and accessibility may increase healthcare [7, 16, 17, 20, 22, 24, 30-41]. Juon et al. [42] in a randomized control trial evaluated the effectiveness of a community based education program in improving HBV knowledge among 877 Asian Americans. They found even a 30-minute educational program can increase the level of knowledge after 6-month follow-up. All previous study recommended extended health educational program and increase the quality of training, but there is a question whether such program can warranty the safety of health care workers.

In the present study, we had large sample sizes, which increase the statistical power. While majority of previous studies conducted in small sample size [7, 19, 34, 40] an important aspect of the current study refers to comparing knowledge in a multicenter survey between tertiary level hospitals of our University. As well as, we tried to review the results of the pervious study about knowledge of hospital staff. Our study, while having much strength, involved some limitations that should be considered [2]. Only individuals who agreed to complete survey were eligible for participation in the study. In fact we did not try to encourage non responder to participate. However, there was no significant difference in demographic characteristics between responders and non responders [1]. We did not coordinate a specific time and place for filling questionnaire, which might decrease the none response rate. Because the most reason for none responding was lack of time.

CONCLUSION

The results of this study indicate a low level of knowledge among HCWs about the hepatitis B and hepatitis C, especially in nature of disease, prevention and treatment strategy. More educated worker reported better knowledge toward viral hepatitis. In spite of the majority of HCWs had NSI education, more than 50% of them reported history of NSI. In service training about universal and standard precaution and also improvement in work condition can decrease the probable risk for health professional.

REFERENCES